Modifying a protein that controls cell growth can reactivate dormant neural stem cells in fruit flies which could help ...

New insights into the role of SUMOylation in the brain could lead to new targeted therapies for neurodegenerative conditions.

Neuroscientists have uncovered a mechanism that controls the reactivation of neural stem cells, which are crucial for repairing and regenerating brain cells. The research offers exciting potential for ...

An international team of neuroscientists, led by Duke-NUS Medical School, have uncovered a mechanism that controls the reactivation of neural stem cells, which are crucial for repairing and ...

An international team of neuroscientists showed for the first time that modifying a protein that controls cell growth can ...

Its lead program is IK-930, an internally discovered, oral, TEAD1-selective, small molecule inhibitor of the Hippo pathway. The company also develops IK-595, a molecular glue designed to trap MEK ...

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Here they show that SUMOylation of Wts, a core Hippo pathway kinase, results in its inactivation and induces NSC reactivation in Drosophila.

Birth of Jesus; shepherds' adoration; Simeon's and Anna's prophecies; return to Nazareth; Jesus among the doctors; ministry of John the Baptist; baptism of Jesus; genealogy of Jesus through Mary. And ...