Modifying a protein that controls cell growth can reactivate dormant neural stem cells in fruit flies which could help ...

Effective prognostic biomarkers for GC were critically needed. Hippo signaling pathway is one of the critical mechanisms regulating the occurrence and development of GC, and has potential clinical ...

New insights into the role of SUMOylation in the brain could lead to new targeted therapies for neurodegenerative conditions.

Neuroscientists have uncovered a mechanism that controls the reactivation of neural stem cells, which are crucial for repairing and regenerating brain cells. The research offers exciting potential for ...

An international team of neuroscientists, led by Duke-NUS Medical School, have uncovered a mechanism that controls the ...

The Hippo pathway, which regulates cell proliferation and apoptosis, presents a therapeutic target for cardiac regeneration. This study explores the efficacy of Lats-IN-1, a LATS1/2 kinase inhibitor ...

An international team of neuroscientists showed for the first time that modifying a protein that controls cell growth can ...

Its lead program is IK-930, an internally discovered, oral, TEAD1-selective, small molecule inhibitor of the Hippo pathway. The company also develops IK-595, a molecular glue designed to trap MEK ...

Types of cell signalling pathways include checkpoint signalling, lipid signalling, growth signalling, nutrient signalling, insulin signalling, stress signalling, morphogen signalling, Hippo ...