A recent review published in eGastroenterology discusses recent advancements in understanding alcohol-associated liver ...

Liver fibrosis is characterized by the excessive accumulation of extracellular matrix components, leading to scarring and impaired liver function. Traditionally linked to viral infections, alcohol ...

Study Finds Targeting Inflammation May Not Help Reduce Liver Fibrosis in MAFLD July 26 ... The Role of Resident Macrophages Apr. 25, 2024 — Researchers discovered liver resident macrophages ...

The Company plans to nominate a development candidate for its liver fibrosis program in the first quarter of 2025, reflecting its expertise in macrophage biology and fibrotic diseases.

Hepatic fibrosis is the common result of injury to the liver from a variety of damaging mechanisms, and the accurate assessment of the degree of fibrosis is clinically important. For many years ...

PHILADELPHIA, PA — Carisma Therapeutics Inc. (Nasdaq: CARM) announced a strategic realignment of its resources, discontinuing ...

Macrophages work alongside neutrophils to ... and transforming growth factor-beta (TGF-β), leading to liver fibrosis. Alcohol stimulates HSCs to produce 2-arachidonoylglycerol (2-AG), which ...

EDINBURGH, Scotland and LONDON, Dec. 10, 2024 /PRNewswire/ -- Resolution Therapeutics Limited ("Resolution" or "Company"), a clinical-stage biopharmaceutical company focused on pioneering ...

A newly published review in eGastroenterology compiles recent research on alcohol-associated liver disease (ALD), offering an overview of its pathogenesis and efforts to better understand this ...