The accumulation of lipids in hepatocytes in nonalcoholic fatty liver disease (NAFLD) leads to an increase in reactive oxygen species and changes in the intracellular microenvironment, while ...

Polycystic ovary syndrome (PCOS) is associated with several mild metabolic disorders, including insulin resistance (IR), obesity, and dyslipidemia, as well as with some more severe ones, including ...

For years, cheese has been unfairly vilified as an unhealthy food choice. However, scientific research is now challenging ...

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous ...

Lithocholic acid is one such secondary metabolite, made by gut bacteria from a bile acid produced by the host. But the idea ...

A MedUni Vienna study has identified a new approach to the drug treatment of metabolic liver diseases. In an experimental ...

Discover recent research that highlights the discovery of 17 novel loci associated with liver triglycerides and 9 linked to ...

Does fructose, one of today's boogeymen, cause cancer? According to a fascinating paper in Nature, it does so in cultured ...

A MedUni Vienna study has identified a new approach to the drug treatment of metabolic liver diseases. In an experimental ...

"Achieving the primary endpoint of a reduction in ALT levels through direct hepatic effects, as well as notable secondary endpoints, including significantly lower HbA1C levels compared to the placebo, ...

Arg1-arginase 1; FA, fatty acid; LD, lipid droplet; LXR, liver X receptor; NFκB, nuclear factor kappa B ... all necessary for shifts in energy metabolism in macrophages, have been shown to be tightly ...