Although kinesins typically use scaffold proteins and adaptor proteins to bind to cargo vesicles ... complexes, which contain mRNA and at least 40 kinds of proteins 61. Fragile X mental ...

Hypothesis: Given proinflammatory mitochondrial DNA (mtDNA) are known to be elevated in HF plasma; and that cells release mitochondrial components in extracellular vesicles, we hypothesize that ...

It has recently been established that GPCR signaling can also take place from intracellular membrane compartments, including endosomes that contain ... endocytic vesicles with 20-30% of the G protein ...

Extracellular vesicles (EVs) have been shown to carry bioactive cargo and have the potential ... Media was then gently aspirated from the wells and replaced with 100 μL cell culture media containing 1 ...

In mammals, autophagosome formation, a central event in autophagy, is initiated by the ULK complex comprising ULK1/2, FIP200, ATG13, and ATG101. However, the structural basis and mechanism of the ULK ...

Eric’s research focused on the dynamic of cell membrane s, and, in particular, on he intracellular systems – the lysosomes, Golgi apparatus endoplasmic reticulum , peroxisomes, and synaptic vesicles – ...

During the vesicular transport including polarized transport, cargos synthesized in the ER have to be transported from the ER by vesicles budded from the ER exit sites ... There is a paper reporting ...