INR:4284. bharat live score RNA therapy combined with innovative delivery technology makes psoriasis no longer "stubborn" Ascentage Pharma's MDM2-p53 Inhibitor ...

Nicknames for commander Revenue ranking of leading overseas pharmaceutical companies in 2020: PD-1 has the highest revenue and PARP has the fastest growth rate! Clinical trials of potential new drugs ...

Overall, this fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. The evidence supporting the ...

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License . Murine double minute 2 (MDM2) is an E3 ligase that inhibits the tumor suppressor ...

He hand-grinds, shapes and custom crafts a set of forged, muscle-back blades that are uniquely yours. A set that’s one-of-one, if you will. We’ve shared some insight into P53 with you before and it’s ...

The membrane was washed with 10 mL of 1 × TBST for 5 min at room temperature and was washed three times. 5 mL of skimmed milk powder blocking solution was incubated at room temperature for 2 h 5 mL of ...

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这种由铜离子介导的细胞死亡过程被称为铜死亡（cuproptosis）【1】。肿瘤抑制因子p53在维持细胞代谢稳态方面发挥重要作用。2023年，周祥团队提出观点，认为铜死亡可能是一种由p53调节的代谢性细胞死亡方式【2】。首先，p53抑制糖酵解过程。例如，该团队早期 ...

This work is licensed under a Creative Commons Attribution 4.0 International License . Missense-type p53 mutations have shown to acquire novel oncogenic roles through gain-of-function mechanism.