定义与结构:PAMAM Dendrimer G2-SA 指的是第二代聚酰胺-胺型树枝状高分子,其表面或末端被琥珀酸(SA)官能团修饰。 特性:由于琥珀酸的引入 ...
Herein, we attempt to employ a functionalized nanoparticle drug carrier system based on polyamine-amine (PAMAM) dendrimers for targeted delivery of resveratrol in hepatocellular carcinoma cancer ...
Nanomedicine. 2012;7(8):1225-1233. Most of the strategies described for the passage of drugs across the BBB can be enhanced by nanotechnology and some of the mechanisms involved include: NPs open ...
PAMAM dendrimers can hold DNA in cavities and act as nonimmunogenic vectors for in vivo gene transfer. The combination of a gene and NP with a surfactant coating can facilitate gene transfer in ...