X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...

Whereas, Paget disease involves thickened and weaker-than-normal bone. The cause is not clear, but some studies suggest that it could be due to genetics and environmental factors. Both the ...

Although abundant evidence of concomitant cardiovascular disease is scattered throughout the literature on osteitis deformans, appreciation of the etiologic relationship between the two diseases has ...

Extramammary Paget’s disease (EMPD), a rare cutaneous tumor with non-specific clinical symptoms, is susceptible to misdiagnosis. This report discusses the case of an older male patient who presented ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...

Heart disease isn't just one thing. It's a number of conditions that can affect how your heart works. Heart disease can also be called cardiovascular disease, though that term covers blood vessels ...

The goal of the MCBDTP is to train PhD and MD/PhD scientists who will advance research in experimental Pathology and the molecular and cellular basis of disease. The MCBDTP provides a PhD training ...

Figure 2: A photomicrograph showing more than 40 nuclear profiles in a giant detached osteoclast, a finding that was previously considered virtually pathognomonic of Paget disease of bone.

Dec. 4, 2024 — New research identifies an association between glyphosate exposure in mice and symptoms of neuroinflammation, as well as accelerated Alzheimer's disease-like pathology.

Resources on the diagnosis, management, and treatment of Parkinson's disease.