Johns Hopkins researchers have developed a powerful new AI tool called "Splam" that can identify where splicing occurs in ...

Their study is published in Genome Biology. "Precisely identifying splicing sites is key to understanding how cells interpret genetic instructions," says co-lead author Kuan-Hao Chao, a doctoral ...

Physiological and morphological changes ultimately rely on variations in gene expression. Alternative splicing, through which multiple transcript variants are produced from a single gene, is one of ...

RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could ...

6Laboratory of Systems Biology and Computational Genetics, Vavilov Institute of General Genetics ... This open access article is distributed under the Creative Commons Attribution 4.0 International ...

Alternative splicing promotes adaptation to environmental changes ... a fungal microbiologist at the Leibniz Institute for Natural Product Research and Infection Biology.

Dec. 19, 2024 — A new role has been uncovered for a cell's own RNA in fending off attacks by RNA viruses. Some of the cell's RNA molecules, researchers found, help regulate antiviral signaling ...

Root-knot nematodes pose a significant threat to agriculture, infecting a wide range of crops and causing billions of dollars ...

This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...