Activation of the Toll-like receptor 4 (TLR4) by bacterial endotoxins in macrophages plays a crucial role in the pathogenesis of sepsis. However, the mechanism underlying TLR4 activation in ...

Their research focuses on a brain protein called CaMKII, which plays a key role in helping us learn and remember things. As we age, this protein doesn’t function as well as it should ...

Background: Sepsis is characterized by high morbidity and mortality rates, alongside limited therapeutic efficacy. Atrial fibrillation (AF), the most common arrhythmia, has been closely linked to ...

Moderate‐intensity treadmill exercise and swimming sessions stimulate STAT3/CaMKII signaling pathway within the mitochondria of mice with diabetic ... transforming growth factor‐beta; TLR4, toll‐like ...