Two gout experts debated whether first-line urate-lowering therapy should consist of a xanthine oxidase inhibitor or should ...

Recursive chemical syntheses were then conducted by exploring SARs using four principal bioassays: renal UA transporters URAT1 (SLC2A22) and splice variants of GLUT9a/b (SLC2A9); xanthine oxidase (XO) ...

The presentation highlights XORTX recent pioneering discoveries in the field of Autosomal Dominant Polycystic Kidney Disease (“ADPKD”), and recent peer-reviewed, independent, published research ...

There were no differences over time in serum oxypurines or purine-containing nucleosides. However, all products increased the fractional excretion of xanthine. Conclusions Intact milk has an acute ...

XORTX Therapeutics (XRTX) announces a presentation by Dr. Allen Davidoff at the Rare and Genetic Kidney Disease Summit, in Boston, ...

Actress Shweta Tiwari's battle with high uric acid and joint pain! Learn how she overcame the condition and regained her ...

We all know Shweta Tiwari's love for coffee and several times the actor has flaunted her passion for coffee on social media.

Genetic testing has enabled early identification of other family members at risk and prevention of renal failure by commencing xanthine oxidoreductase (XOR) inhibitors. The issues surrounding kidney ...

IT is well known that the activity of catalase is greatly inhibited by very small concentrations of potassium cyanide, hydrogen sulphide and especially hydroxylamine. To these reagents we can now ...

“This gene-to-molecule research is crucial for discovery in Alzheimer’s disease. It offers fresh perspectives on how genetic risk factors, such as APOE, influence metabolism and perhaps disease ...

There are currently five drugs approved by the U.S. Food and Drug Administration (FDA) to reduce uric acid levels. Commonly prescribed urate-lowering therapies include: Zyloprim (allopurinol): This ...