A new study has uncovered a surprising player in ketamine’s rapid antidepressant effects: astrocytes, the star-shaped support ...

Astrocytes are star-shaped glial cells in the central nervous system that support neuronal function, maintain the blood-brain ...

Data and codes supporting the manuscript "Dialogue mechanisms between astrocytic and neuronal networks: a whole-brain modelling approach" by Ali et al., 2024, PCBI.

Although CB1Rs were originally thought to reside mainly on presynaptic axon terminals, several studies have highlighted an unexpected role for astrocytic CB1Rs in endocannabinoid mediated plasticity.

Here, we show that astrocytes across the mouse SCN exhibit instead a highly uniform, pulse-like nighttime activity. We find that rhythmic astrocytic GABA production via polyamine degradation provides ...

Sleep deprivation (SD) contributes to cognitive impairment. Astrocytic cholesterol biosynthesis is crucial for brain cholesterol homeostasis and cognitive function. However, the underlying mechanism ...

NGS enables rapid, cost-effective genetic analysis, transforming the diagnosis and management of ocular cancers like retinoblastoma. Differentiating hereditary from nonhereditary retinoblastoma is now ...

Center for Global Biopharmaceutical Research, Korea Institute of Toxicology, Daejeon 34114, South Korea Human and Environmental Toxicology, University of Science and Technology, Daejeon 34113, South ...