Scientists have has pioneered antivirals targeting viral methyltransferases, offering a new strategy for treating RNA and DNA ...

RNA capping relies on enzymes called methyltransferases—making it a tempting target for antiviral therapies. But most ...

Today's health news in STAT Morning Rounds includes HHMI's new eligibility criteria, the latest on a California bird flu ...

揭示H3K4me3修饰在动物早期胚胎发育中建立及调控功能近日，华中农业大学动物科学技术学院、动物医学院苗义良教授领衔的动物克隆与干细胞研究团队研究成果以“Histone methyltransferases MLL2 and SETD1A/B ...

By deducing the possible ancient forms of a bacterial enzyme, OIST scientists have resurrected one of its ancestral versions, ...

The arrival of Paxlovid in December 2021 marked another turning point in the COVID-19 pandemic-;an effective antiviral that has since successfully treated millions.

During parasitoid wasp infection, activated immune cells of Drosophila melanogaster larvae release adenosine to conserve nutrients for immune response. S-adenosylmethionine (SAM) is a methyl group ...

Researchers have introduced a proof-of-concept for a new class of antivirals that could be used against RNA viruses including ...

Drug (purple) that inhibits viral mRNA cap methyltransferase NSP14 for antiviral therapy. Drug binding requires the presence ...

Methods The methylation status of endogenous Wnt antagonists in leucocytes and fibroblasts was evaluated by methylation-specific PCR. 5-aza-2′-deoxycytidine was used to inhibit DNA methyltransferases ...