A study carried out at the University of Helsinki shows how a single gene in Atlantic salmon can dramatically influence the ...

Methods: Based on the Genome-Wide Association Studies (GWAS) summary data sets, the Inverse variance weighted (IVW) method was used as the main method, the weighted median method and MR-Egger method ...

The results of this manuscript look at the interplay between pleiotropy, standing genetic variation, and parallelism (i.e. predictability of evolution) in gene expression. Ultimately, their results ...

Limitations include potential pleiotropy, lack of sex-based stratification, and collider bias, which may confound results. Obesity is identified as a modifiable risk factor, suggesting potential ...

IVW analysis indicated an increased risk of NAFLD associated with WHR (OR = 1.61; 95% CI: 1.08–2.41; P = 0.02). Furthermore, MR-Egger regression analysis revealed the absence of horizontal pleiotropy ...