Osteoporosis (OP) stands as the most prevalent systemic skeletal condition associated with aging. The current clinical management of OP predominantly depends on anti-resorptive and anabolic agents.
Kan et al. report the discovery of a Bacillus amyloliquifaciens strain that kills Nerisseria gonorrhoeae via oxydifficidin which targets ribosomal proteins. Resistance occurred via mutation in the ...
Chemical biologists studying natural-product pathways encoded in genomes have unearthed new chemistry and insights into the evolution of biologically active metabolites.
相关工作以题为“Hybrid Type I and II Polyketide Synthases Yield Distinct Aromatic Polyketides”发表在J. Am. Chem. Soc.上。南京大学生命科学学院博士生赵丽娅和助理教授史净为文章的共同第一作者,戈惠明教授、焦瑞华教授和史净助理教授为通讯作者。该研究得到了国家自然科学 ...