Extracting exons from pre-mRNA and splicing them together to create mRNA requires, first and foremost, a mechanism for distinguishing exons and introns. Intron recognition always takes place ...

This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...

How does the splicing machinery distinguish between exons, which are part of the mature mRNA, and introns, which are removed from the pre-mRNA? Alternative splicing adds an extra layer of ...

A new study has uncovered the complex genetic interaction between root-knot nematodes and tomato plants, revealing how these ...

Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, ...

The German gene therapy developer will test VG801 in patients with Stargardt disease and other retinal dystrophies linked with ABCA4 mutations.