This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...
The present study utilized advanced LNP technology to deliver VEGF mRNA to the placenta, targeting the underlying dysfunction in pre-eclampsia. The researchers screened 98 LNP formulations using ...
In her latest study, published in Nature, Swingle examined 98 different LNPs and their ability to get to the placenta and decrease high blood pressure and increase vasodilation in pre-eclamptic ...
RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...
When the team used the most promising of these LNPs to deliver mRNA molecules coding for VEGF to pregnant mice with pre-eclampsia, the mice’s blood pressure returned to normal for the ...
But, by laying this groundwork, Swingle's work has not only identified an avenue for curing pre-eclampsia, it also opens doors for research on LNP-mRNA therapeutics addressing other reproductive ...
Engineers have developed a lipid nanoparticle (LNP) that delivers mRNA therapeutic to the placenta to treat pre-eclampsia in mice with human trials on the horizon. Penn Engineers have made a ...
CBSE Class 10 English Pre-Board Exam 2025: Pre-board exam is an important academic journey. It helps you assess your preparation level and identify areas that require more attention. This sample ...