"Our team has created a targeted prodrug (a compound which metabolizes inside the body into a pharmacologically active drug), ...

Results from the company’s Phase I trial found its prodrug, SPT-300, was well tolerated, opening the doors to a Phase IIb ...

Consequently, the success of prodrug strategies are very powerful means to improve formulation and delivery properties of drugs. However, prodrug intervention must be an integral part of the drug ...

The grant focuses on a promising new prodrug, CTT2274, that targets Prostate-Specific Membrane Antigen (PSMA) on prostate cancer and is designed to release a toxic drug, MMAE, within the cell that ...

A prodrug of galantamine and an acetylcholinesterase inhibitor (AChEI), benzgalantamine has a dual mechanism of action designed to eliminate drug absorption in the gastrointestinal (GI ...

A phase 3 prostate cancer trial of Candel’s oncolytic virus has met its primary endpoint, sending the stock up more than 200% ...

Lipocine Inc. (NASDAQ: LPCN), a biopharmaceutical company leveraging its proprietary technology platform to augment therapeutics through effective oral delivery, today announced that the U.S. Food and ...

We are pleased to have published results from our Phase 1 MAD study of MBX 2109 in JCEM, a leading peer-reviewed journal of endocrine and metabolic research,” said Kent Hawryluk, President and Chief ...

The company’s lead drug candidate, MIV-818, is a liver cancer targeted prodrug that Medivir is looking to develop alone in the USA and the EU and through partnerships elsewhere. Swedish ...

Cancer Targeted Technology LLC has been awarded the phase I portion ($400,000) of a fast track phase I/II ($2.4 million) Small Business Innovation Research (SBIR) grant by the National Cancer ...

And how does that affect its activity? Dr. Sabatine: Clopidogrel is a prodrug and it needs to be activated through sequential oxidative steps in the liver (Slide 1). There is another pathway where ...