During a Case-Based Roundtable® event, Andrew H. Lipsky, MD, moderated a discussion on the efficacy and safety of newer BTK ...
Initiated Phase 1b dose expansion of NX-5948 in chronic lymphocytic leukemia patient population with Fast Track Designation from the FDAInitiated ...
智通财经APP获悉 ,平安证券发表研报称,BTK 抑制剂的问世是血液瘤治疗的重大突破,二代 BTK 抑制剂凭借更优疗效和安全性,市占率逐年提升。我国每年新发淋巴瘤患者10万人,虽然从发病率远低于一些实体瘤如肺癌,然而该领域靶向疗法的出现,使得临床治疗中淋巴瘤已然可视为慢病管理。患者基数及管理周期长叠加下,血液瘤领域相继出现多款突破十亿美元重磅分子如伊布替尼、泽布替尼、阿卡替尼、维奈克拉等,凸显出不 ...
Exscientia plc (Nasdaq: EXAI) today announced three abstracts to be presented at the 36th EORTC-NCI-AACR (ENA) Symposium 2024 ...
AstraZeneca’s supplemental New Drug Application (sNDA) for CALQUENCE ® (acalabrutinib) has been accepted and granted Priority Review in the US for the treatment of adult patients with previously ...
The iPhone 16 Pro Max stands atop our best phones list, and the standard iPhone 16 isn't too far behind. But really, any device from the iPhone 16 lineup will serve you will, thanks to powerful ...
Don't miss out on the headlines from QLD News. Followed categories will be added to My News. Briony Benjamin was diagnosed with stage four lymphoma in 2018 at the age of 31 while she was working ...
About 1% to 3% of stomach (gastric) cancers are hereditary diffuse gastric cancers (HDGC). The disorder is caused by mutation in the CDH1 gene. HDGC is an inherited cancer syndrome that leads to an ...
Copy and paste should be easy enough, but I know from experience when you try to copy files quickly, especially numerous files, Windows doesn’t always cooperate. If it’s not going well, We have got a ...
A crucial protein in the formation of B-cell lymphoma and CLL is called Bruton’s tyrosine kinase. “There are already BTK inhibitor drugs approved by FDA to control lymphoma and CLL,” Khawaja said.
据悉,该新药为集团自主研发的小分子创新药,拟用于治疗血液系统恶性肿瘤,尤其是以弥漫性大B细胞淋巴瘤(DLBCL)为主的B细胞淋巴瘤。截至目前的临床前研究显示,该新药在多种血液肿瘤模型中展现出较为显著的抑制肿瘤生长的药效且安全性良好,有望解决既往BTK共价抑制剂治疗并产生耐药的问题。