These include effects on arterial smooth muscle cells that cause intense peripheral vasoconstriction and stimulation of cardiac myocytes and fibroblasts. The latter promotes phenotypic changes in ...

Objectives To study the expressions of endothelin-converting enzyme (ECE2) at early stages of atrial fibrillation in a rapid paced primary cultured atrial myocyte model. Methods Primary rat atrial ...

Several observations from preclinical and short-term clinical studies support a role for sildenafil in the treatment of heart failure patients. The following discussion briefly considers each of ...

The researchers were able to show ... Analysis Reveals an Additional Mechanism Behind Statin Therapy's Heart-Related Benefits in People With HIV Dec. 11, 2024 — Investigators who previously ...

Obesity is associated with an increased risk of heart failure. Apparently healthy obese individuals can, however, exhibit subclinical left ventricular dysfunction. The use of myocardial imaging ...

It may sound dramatic, but the rate at which your heart is beating plays a key role in how long you’re likely to live. According to expert cardiologists and academic researchers, resting heart ...

Diagnosis. Stress-induced (Takotsubo) cardiomyopathy (apical ballooning syndrome). Management. The patient was monitored with cardiac telemetry. Metoprolol and ramipril were continued.