Exicure, Inc. (Nasdaq: XCUR, “Exicure”, “the Company”), has announced the signing of a Memorandum of Understanding (MOU) with ...

Superior quality cytokines are crucial for reliable research results and the safe production of cancer cell therapies.

Cys-loop receptors are ligand-gated ion channels with two domains connected by a short linker. The top domain is located extracellularly, while the bottom domain sits in the cell membrane.When an ...

Given the newfound role of NRP1 in nerve growth factor pain signaling, the researchers envision several ways that this knowledge can be used to redeploy existing therapies to treat pain and create ...

One avenue for this ambition is cell receptors, which function like ignition slots on a cell, requiring keys—such as specific hormones, drugs, or antigens—to start up specific cellular activities.

School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, ...

State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China ...

2020). In the complex signaling transduction process, Protein kinase C (PKC) is a key effector molecule within the G protein-coupled receptor system. Figure 2. Oxidative stress pathways in CI-AKI. CM ...

Innate immune signaling pathways of TLRs, IL1-Rs, and TNFRs ... as well as reduced transcription of chemokines CCL2 (MCP1), CCL3 (MIP1α), and chemokine receptor CX3CR1. Consequently, the infiltration ...

This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets by Stacey D. Gilk, Rajendra Angara and Arif Sadi. The ...

Department of Internal Medicine (Q.S., J.W., H.M., X.L., J. Streeter, J. Sharafuddin, E.W., B.C., D.H., L.-S.S., E.D.A.), Carver College of Medicine, University of ...