Cys-loop receptors are ligand-gated ion channels with two domains connected by a short linker. The top domain is located extracellularly, while the bottom domain sits in the cell membrane.When an ...
Given the newfound role of NRP1 in nerve growth factor pain signaling, the researchers envision several ways that this knowledge can be used to redeploy existing therapies to treat pain and create ...
One avenue for this ambition is cell receptors, which function like ignition slots on a cell, requiring keys—such as specific hormones, drugs, or antigens—to start up specific cellular activities.
School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, ...