This protein is synthesized in hepatocytes and secreted as the holoprotein with six atoms of copper incorporated during transit through the late secretory pathway. Although copper has no effect on ...

Researchers have identified that the status of the T-cell Golgi apparatus is a key indicator of performance in cancer immunotherapy approaches. A group of researchers working at the Medical University ...

This molecule interacts with STING, facilitating STING’s translocation from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment and ultimately to the Golgi apparatus. This ...

Glycosylation, which plays an important role in modifying lipids and sorting of proteins, is regulated by asymmetric intra-Golgi distribution and SPPL3-mediated cleavage of Golgi enzymes. We found ...

Figure 1. Overview on the intracellular metabolic pathways of Cu homeostasis. Extracellularly, Cu(II) are reduced to Cu(I) by metal reductase; intracellular Cu(I) are transported to nucleus, Golgi ...

The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the ...

EXPERIMENTS have been made with five specimens of methylene blue as a vital stain for the spermatocytes of Helix aspersa. The specimens were an old German ‘polychrome methylene blue', and four ...

The design principles dictating the spatio-temporal organisation of eukaryotic cells, and in particular the mechanisms controlling the self-organisation and dynamics of membrane-bound organelles such ...