Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders ...
"However, it has been unknown, under hypoxia, whether and how HIF1α regulates IFN-γ induction and glycolysis ... Department of Defense-Congressionally Directed Medical Research Programs grant ME210108 ...
According to the 10th edition of the IDF Diabetes Atlas, 537 million people suffered from diabetes in 2021, and this number will increase by 47% by 2045. It is estimated that even 30-40% of these ...
The liver is one of the organs in which hypoxia helps to regulate gene expression under normal physiological conditions, as well as diseases such as cirrhosis and cancer. Hypoxia enhances ...
1 Department of Psychiatry, Dalian Seventh People’s Hospital, Dalian, China 2 Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, China Introduction: Sleep ...
Tui Airways flyers were put at risk of hypoxia — a lack of blood oxygen that can be life-threatening — after “bleed switches” were left off, preventing the cabin from pressurizing ...