Salient differences of Bartonella IE-associated glomerulonephritis include delayed onset to kidney biopsy, frequency of serological markers of inflammation, including ANCA (75%) and RF positivity (84% ...

The herpes IgG test is a blood test used to diagnose herpes simplex virus (HSV). This includes HSV-1, the type most commonly linked to cold sores, and HSV-2, the type mainly associated with genital ...

Background Since there is evidence that the Fc domain of antivascular endothelial growth factor drugs may cause unexpected consequences in retinal and choroidal vessels, the effects of intravitreal ...

A very rare subset of ENGases specifically hydrolyze the Asn297-linked glycan on the fragment crystallizable (Fc) region of immunoglobulin G (IgG) antibodies, a major molecular determinant for Fc ...

Experimental blockade of ACK1 or BRK increased circulating autoantibodies in vivo in mice and exacerbated glomerular IgG deposits in an SLE mouse model. Mechanistically, non-receptor tyrosine kinases ...

IgE is an antibody that plays a key role in allergic responses. It can sometimes also be elevated for other reasons, such as chronic infections or inflammatory diseases. When your IgE levels are high, ...

The classical pathway is activated, primarily on mucosal surfaces, by binding of the C1 complex (C1q, C1r, and C1s) to surface‐bound immune complexes, mainly IgG or IgM (57). C1 activation initiates ...