(RTTNews) - Vanda Pharmaceuticals Inc. (VNDA) Friday announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation for VGT-1849A, a selective antisense oligonucleotide ...

Articles on myeloproliferative neoplasms (MPNs) covered the debate over how early to use cytoreductive therapies instead of ...

1These novel variants, classified by the WHO as variants of interest (VOI) or, in the worst cases, variants of concern (VOC), are characterized by a persistent accumulation of mutations primarily in ...

[18] Factor V Leiden (12%) Factor V Leiden mutation is more resistant to activated protein C and therefore takes longer to switch off clotting. Clotting is tested in the presence and absence of ...

No significant differences in red blood cell levels were observed, however. All patients in the study had JAK2 V617F mutations but only 12 had FVL mutations. The FVL mutations accounted for 5% of PV ...

However, recent human cases of H5N1 in British Columbia in Canada and California have increased concerns about the adaptability of the virus and possible mutations that could facilitate human-to ...

There are 3 main types of MPN disorders, with most driven by mutations in Janus kinase (JAK2); this mutation accounts for 90% of patients with polycythemia vera (PV), 60% of patients with ET ...

Expert Rev Mol Diagn. 2012;12(5):511-526. Fragment analysis discriminates PCR products based on size and is useful for the detection of mutations, such as insertions, deletions and duplications ...

This review makes a detailed introduction to the mutation characteristics of SARS-CoV-2, focusing on the molecular mechanism of mutation affecting the infectivity of SARS-CoV-2, and the impact of ...

The guidelines mention only one BRCA1 RPPV at present. "What we're saying in our paper is that there are some BRCA1 and BRCA2 mutations that really don't warrant the same management recommendations as ...