We found that ADGRA3 facilitates the biogenesis of beige adipocytes through the Gs-PKA-CREB axis. Moreover, hesperetin was identified as a potential agonist of ADGRA3, capable of inducing adipocyte ...

At the molecular level, Semaglutide’s interaction with GLP-1 receptors is hypothesized to stimulate cyclic adenosine monophosphate (cAMP) production, which in turn may activate protein kinase A (PKA) ...

This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets by Stacey D. Gilk, Rajendra Angara and Arif Sadi. The ...

We found that ADGRA3 facilitates the biogenesis of beige adipocytes through the Gs-PKA-CREB axis. Moreover, hesperetin was identified as a potential agonist of ADGRA3, capable of inducing adipocyte ...

Over the past couple of decades, it has become apparent that skeletal muscles might be engaged in endocrine signaling, mostly as a result of exercise or physical activity in general. The importance of ...

In INSIE cells and fibroblasts, S1P affects cAMP levels and the MAPK pathway, influencing PKA activity and inflammatory responses mediated by MKP-3, ERK1/2, NF-κB, TNF-α, and IL-6. These interactions ...