Nowadays, we know that lysosomes contain hydrolases that are capable ... electron microscopes and discovered a wide variety of vesicles. Some of the vesicles contained engulfed cytoplasmic material.

storage vesicles, or the plasma membrane (Figure 2). Lysosomes break down macromolecules into their constituent parts, which are then recycled. These membrane-bound organelles contain a variety of ...

Recent studies suggest that these granules can "hitch a ride" from lysosome-related vesicles, membrane-bound structures in ...

They identified two distinct modes of endosomal fusion: homotypic fusion, where two endosomes fuse rapidly to form a single ...

I am a cell physiologist and my research lab uses genetics, biochemistry, advanced microscopy and synthetic biology to study: (1) fundamental lysosome biology in health and disease, and (2) ...

In mammals, autophagosome formation, a central event in autophagy, is initiated by the ULK complex comprising ULK1/2, FIP200, ATG13, and ATG101. However, the structural basis and mechanism of the ULK ...

APOE genotype was shown to influence vesicle trafficking pathways in aged APOE Targeted Replacement mice, with APOE2 and APOE4 appearing to have opposite effects when compared with APOE3. More ...

Lysosomes are organelles of the living cell that contain digestive enzymes. They play an important part in normal life processes, and there is evidence that they are also involved in pathological ones ...

Retraction Note: M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade. Retraction Note ...

Why Is Temu So Cheap? Temu’s prices are indeed shockingly low. So low that they can’t help get your attention and cause you to throw things in your cart. It seems that Temu is trying to ...

Italian Prosecutors who have opened up a criminal probe into multiple charges of manslaughter and negligent shipwreck think the 56-meter (184-foot) yacht, the Bayesian, may contain highly ...