Solve Therapeutics Inc. has identified antibody-drug conjugates comprising an UC-961 antibody or a tyrosine-protein kinase transmembrane receptor ROR2 (ROR2)-targeting antibody covalently linked to ...
Peptides, as versatile biological molecules, have garnered significant attention in scientific research due to their ...
By enhancing the clearance of neutrophil extracellular traps (NETs) through the AMP-activated protein kinase (AMPK)/scavenger ...
A cutting-edge study has identified medical ozone therapy as a promising new treatment for sepsis-induced acute lung injury (ALI). By enhancing the ...
Arvinas focuses on protein degradation, with its lead candidate, ARV-471, in Phase 3 trials for breast cancer. Read why we ...
Cellular research indicates that neuropilin-1 plays a crucial role in pain signaling, presenting a potential pathway for ...
The study highlights adhesion G-protein-coupled receptor A3 (ADGRA3) as a potential target for activating adaptive thermogenesis ... (F and H) Western-blot analysis for level of p-CREB and CREB ...
HMBD-001 is under clinical development by Hummingbird Bioscience and currently in Phase I for Pancreatic Ductal Adenocarcinoma.
The authors declared no competing interests. Cite this: The Role of Hormonal Therapy in the Management of Hormonal-Receptor-Positive Breast Cancer With Co-Expression of HER2 - Medscape - Sep 01 ...
For the organism it is important to replenish internal energy storages selectively and selective appetite for nutrients might uncover internal energy requirements. How is the selective uptake of a ...
抗体药物偶联物(antibody-drug conjugate,ADC)是一类由单克隆抗体和小分子细胞毒药物通过连接子偶联而成的靶向治疗药物。 ADC在进入体内后,与肿瘤特异性抗原结合,形成ADC-抗原复合物;复合物通过内吞作用进入肿瘤细胞,经由内体-溶酶体途径连接子被切断,释放细胞毒药物,介导肿瘤细胞凋亡。