In patients with protein C and protein S deficiency, when warfarin therapy is started there is a more rapid fall in concentration ... such as factor IX and X and prothrombin.

Moreover, prothrombin as well as factor V is not increased in parallel, and plasma albumin is even decreased. 15 Also, factors VII and X and the "complex" do not always move in parallel.

Studies shown that prothrombin time (PT) or international normalized ratio (INR ... Previous clinical experiences indicate that BDF poisoning is primarily managed with vitamin K1, though treatment ...

11,12 It has also been established that subjects may vary widely in prothrombin response to a given concentration of Dicumarol in plasma. "Sensitive" patients may exhibit marked ...