A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...
This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...
One key discovery was the influence of chromatin topology, which refers to the folding and looping of DNA within the nucleus. These structures guide TFs along DNA pathways or concentrate them at ...
New findings in mice have uncovered a crucial mechanism linking neuronal activity to mitochondrial function, researchers report, revealing a potential pathway to combat age-related cognitive decline.