SAN DIEGO -- Results from a small single-center study showed that treatment with a gene therapy involving the use of ...

Research led by Christian Medical College in Vellore, India, has demonstrated the successful use of lentiviral vectors to ...

Autologous HSCs were transduced with CD68-LV-ET3 — a lentiviral vector including a new F8 transgene (ET3) with a myeloid-directed CD68 promoter — either without transduction enhancer (group 1 ...

Researchers study long-term safety of lentiviral gene therapy in primates, finding no evidence of somatic mutations or ...

Integrated gene therapy successfully treated Haemophilia A in India, providing long-term relief without bleeding episodes for ...

Current lentiviral vector systems (the third generation) generate virus particles using four plasmids and a producer cell line. The rationale behind four plasmids is to enhance safety, as ...

SAN DIEGO -- Results from a small single-center study showed that treatment with a gene therapy involving the use of lentiviral vector-transduced autologous hematopoietic stem cells (HSCs ...

1996a) (Naldini et al., 1996b) , the vector pCMVΔR8.2 supplies all but the HIV envelope in trans, the vector pMD.G is used to produce the VSV-G pseudotype, while the transgene (lac Z) is inserted into ...

Download this application note from Thermo Fisher Scientific to learn how scientists have used their lentiviral production system, single-use bioreactors, and clarification products to generate ...

In a significant medical feat, Indian scientists have developed the first-in-human gene therapy using lentiviral vectors for ...

ESO-T01 is the first in vivo BCMA CAR-T candidate to reach the clinical stageEarly clinical data are expected in second half of ...

Haemophilia is a severe bleeding disorder caused by the deficiency of clotting Factor VIII, leading to spontaneous internal ...