Results from a small single-center study showed that treatment with a gene therapy involving the use of lentiviral ...

Research led by Christian Medical College in Vellore, India, has demonstrated the successful use of lentiviral vectors to ...

Researchers study long-term safety of lentiviral gene therapy in primates, finding no evidence of somatic mutations or ...

Autologous HSCs were transduced with CD68-LV-ET3 — a lentiviral vector including a new F8 transgene (ET3) with a myeloid-directed CD68 promoter — either without transduction enhancer (group 1 ...

Current lentiviral vector systems (the third generation) generate virus particles using four plasmids and a producer cell line. The rationale behind four plasmids is to enhance safety, as ...

Will support the execution of a robust pipeline of customer projects for innovators developing groundbreaking in vivo and ex ...

In a significant medical feat, Indian scientists have developed the first-in-human gene therapy using lentiviral vectors for ...

Download this application note from Thermo Fisher Scientific to learn how scientists have used their lentiviral production system, single-use bioreactors, and clarification products to generate ...

1996b) , the vector pCMVΔR8.2 supplies all but the HIV envelope in trans, the vector pMD.G is used to produce the VSV-G pseudotype, while the transgene (lac Z) is inserted into the plasmid pHR’, which ...

ESO-T01 is the first in vivo BCMA CAR-T candidate to reach the clinical stageEarly clinical data are expected in second half of ...

Integrated gene therapy successfully treated Haemophilia A in India, providing long-term relief without bleeding episodes for ...

Haemophilia is a severe bleeding disorder caused by the deficiency of clotting Factor VIII, leading to spontaneous internal ...