The 49ers' slim postseason hopes came crashing down in Week 16.

ESPN's Football Power Index rates the 49ers' playoff chances at less than 1% entering Week 16, making it extremely unlikely ...

The Dallas Cowboys and San Francisco 49ers were knocked out of playoff contention before either of them took the field Sunday ...

Brock Purdy is due for a big contract soon, but one reporter on the San Francisco 49ers beat doesn't think he'll be offering ...

Brock Purdy had his team in position for a comeback win but came up short in the city of his childhood hero Dan Marino.

Tua Tagovailoa threw the 100th passing touchdown of his career, and the Miami Dolphins defeated the San Francisco 49ers on ...

NFL results and highlights as the Washington Commanders and Minnesota Vikings sealed thrilling late wins while the San ...

The Detroit Lions (13-2) and San Francisco 49ers (6-9) meet at Levi's Stadium in Week 17 for Monday Night Football. Kickoff ...

The Dallas Cowboys and San Francisco 49ers were expected to be among the top contenders to represent the NFC in Super Bowl ...

Former NFL star Richard Sherman has given his take on what needs to change for his former team, the San Francisco 49ers, ...

The Detroit Lions can move one step closer to tying up top spot in the National Football Conference when they travel to the ...

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Sunday football game between San Francisco 49ers ...