A research team have recently published their article, "Rationally designed pooled CRISPRi-seq uncovers an inhibitor of ...

Soil plays a much bigger role in the spread of antibiotic resistance than one might imagine. Surprisingly, the ground beneath us is packed with antibiotic resistance genes (ARGs)—tiny codes that ...

weakly electrophilic cysteine-reactive fluoroamidine warhead into mRNA display libraries and screen these to discover potent and selective covalent cyclic peptide inhibitors of peptidyl arginine ...

Figure 1. The flow chart of patient enrollment for this study. LAA stroke, large artery atherosclerotic (LAA) stroke; IL, interleukin; MPO, myeloperoxidase; PAD4, Peptidyl arginine deiminase-4; HMGB1, ...

Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Neutrophils are essential components of the innate immune system that defend ...

Therefore, NENs possess unique properties such as secreting physiologically active amines and peptidyl hormones which allow NENs to retain unique methods for identification.1 3 In rare instances, NENs ...

Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell nuclei all at the same time. The method, called ChIP–DIP (Chromatin ...

MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, U.K.

Ang-II (angiotensin II) impairs the function of the antihypertensive enzyme ACE2 (angiotensin-converting enzyme 2) by promoting its internalization, ubiquitination, and degradation, thus contributing ...

Sung JS, Jung J, Kwon S, Bae HE, Kang M-J, Jose J, Lee M, Cho S, Chu MK, Pyun J-C (2024) One-step Ultra-Rapid Immunoassay of Calcitonin Gene-Related Peptide for Migraine Diagnosis. Biosens Bioelectron ...