Calmodulin - Wikipedia
Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. [1] It is an intracellular target of the secondary messenger Ca 2+, and the binding of Ca 2+ is required for the activation of calmodulin.
Calmodulin Binding Proteins and Alzheimer’s Disease: …
The role of calmodulin in the function of stromal interaction molecule 2 (STIM2) and adenosine A2A receptor, two other proteins linked to neurodegenerative events, is discussed. Prior to concluding, an analysis of how targeting calmodulin and its binding proteins are viable routes for Alzheimer’s therapy is presented.
钙调蛋白 - 百度百科
钙调蛋白（calmodulin, CaM）又称钙调素，是一种普遍存在于各种真核细胞内，并能与钙离子结合的多功能蛋白质。 钙调蛋白参与细胞内多种信号转导途径，并在Ca2+依赖性信号转导途径中起到关键作用，是动态Ca2+传感器，能够响应广泛的Ca2+浓度，并向下游传递信号。
Calmodulin | Clinical Center - National Institutes of Health
The primary mediator of Ca 2+-dependent signaling in eukaryotic cells is calmodulin, which serves as a high affinity intracellular Ca 2+ receptor. Calmodulin is a ubiquitous, highly conserved protein that plays a critical role in numerous essential cellular functions, including Ca 2+ transport, cell motility, cytoskeletal assembly, protein ...
Phytochemical Interactions with Calmodulin and Critical Calmodulin …
2023年4月15日 · Some phytochemicals bind to and inhibit calmodulin directly while others bind to and regulate calmodulin-binding proteins, including Aβ monomers and BACE1. Phytochemical binding to Aβ monomers can prevent the formation of Aβ oligomers. A limited number of phytochemicals are also known to stimulate calmodulin gene expression.
钙调蛋白 - 维基百科，自由的百科全书
钙调蛋白（英語： Calmodulin ，简称CaM），又稱為攜鈣素，是一種能与钙离子结合的蛋白质，普遍存在真核生物 细胞中。 钙调蛋白是一种多功能中介钙结合蛋白。
Calmodulin: an introduction - Canadian Journal of Biochemistry …
Calmodulin is the most widely distributed and most versatile member of a family of calcium-binding proteins which probably serve as receptors for the Ca 2+ signal. Through the regulation of a wide variety of intracellular enzymes, calmodulin plays a key role in …
Calmodulin - an overview | ScienceDirect Topics
Calmodulin is important in many neuronal processes, including transduction of calcium signaling, regulation of neurotransmitter receptors and ion channels, and neuronal plasticity (McCue et al., 2010; Sandhir and Gill, 1994). Calmodulin has four binding sites at …
Calmodulin: a prototypical calcium sensor - ScienceDirect
2000年8月1日 · Calmodulin is the best studied and prototypical example of the E–F-hand family of Ca 2+ -sensing proteins. Changes in intracellular Ca 2+ concentration regulate calmodulin in three distinct ways. First, at the cellular level, by directing its subcellular distribution.
Calmodulin - Definition, Function and Structure - Biology Dictionary
2017年7月4日 · Calmodulin, or calcium-modulated protein, is a calcium-binding protein found in the cytoplasm of all eukaryotic cells. It interacts with many other proteins in the cell, and acts as a regulator or an effector molecule in a wide variety of cellular functions.
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