A chemostat can be operated at dilution rates higher than the (maximum) specific growth rate when cell cycle is used.
The steady-state cell concentration in a chemostat is increased by a factor of (1+a-aC) by cell recycle. (Not exactly!) Compare Eq.(11) with the productivity without cell recycle. Cell concentrations and productivities are higher with cell recycle, …
Cell Recycle - an overview | ScienceDirect Topics
To keep the cell concentration higher than the normal steady state level in a chemostat, cells in the effluent can be recycled back to the reactor. The cell recycle increases the rate of conversion (or productivity) and also increases the stability of some systems (eg, wastewater treatment) by minimizing the effects of process perturbation.
This lecture covers: theory of the chemostat, fed batch or semi-continuous fermentor operations Biological Reactors (Chemostat) Concentration/Combustion constant Biological CSTR [S] 0 V F F [S], x Figure 1. Diagram of a chemostat. F = Volumetric flow rate biomass x= volume [S] 0 = Concentration of growth limiting substrate. (for growing cells)
Modified Bioreactors: Chemostat with Recycle To keep the cell concentration higher than the normal steady-state level, cells in the effluent can be recycled back to the reactor. Advantages of Cell Recycle 1. Increase productivity for biomass production 2. Increase stability by dampening perturbations of input stream properties 10
- Compare with our solutions for CSTR without cell recycling - These are generic solutions applicable for both with & without cell recycling as long as the bioreactor is a steady state CSTR
A chemostat can be operated at dilution rates higher than the (maximum) specific growth rate when cell cycle is used.
Modified types of the above modes are fed-batch, chemostat with recycle, multi-stage continuous reactors Chemostat with Cell Recycle Designed to keep the cell concentration higher than the normal steady state level in a chemostat. To increase the cell and growth associated product yield
Application of a partial cell recycling chemostat for continuous ...
2019年3月25日 · The partial cell recycling chemostat is a modification of the chemostat in which cells are partially recycled towards the bioreactor. This allows using dilution rates higher than the maximum growth rate resulting in higher biomass concentrations and increased process rates.
Chemostat With Cell Recycle | PDF | Chemistry - Scribd
Chemostat With Cell Recycle - Free download as Powerpoint Presentation (.ppt / .pptx), PDF File (.pdf), Text File (.txt) or view presentation slides online. The document discusses cell recycle processes which involve returning biomass from downstream of a fermentation process back to …