Salicylic Acid: The Journey From Humble Willow to Aspirin
2014年7月24日 · In 1828 German chemist and professor Joseph Buchner isolated yellow crystals from willow extract – on a Buchner funnel, perhaps? I have no idea if it was named after him, but I vote “yes” – and named the crystalline compound “salicin,” after the genus of the willow tree, Salix .
Medicinal potential of willow: A chemical perspective of aspirin ...
2010年7月1日 · The willow tree is a symbolic medicinal plant that has been associated with the discovery of aspirin, chemically known as acetylsalicylic acid, or salicylate, which still offers surprises as a revival drug.
(PDF) Medicinal potential of willow: A chemical ... - ResearchGate
2010年7月1日 · The willow tree is a symbolic medicinal plant that has been associated with the discovery of aspirin, chemically known as acetylsalicylic acid, or salicylate, which still offers surprises...
The historical analysis of aspirin discovery, its relation to the ...
For several millennia, the willow tree and salicin have been associated with salicylic acid, the key precursor molecule that has contributed to the discovery of acetylsalicylic acid, traded as aspirin. These molecules have been shown to possess phyto‐ and chemotherapeutic activities as analgesic drugs.
Phytochemistry, Pharmacology and Medicinal Uses of Plants of …
Willow bark extract (A pharmaceutically used extract BNO 1455) and its fractions (flavonoids, proanthocyanidins, salicyl alcohol derivatives) showed dose dependent cytotoxic effects against human colon and lung cancer irrespective of their COX-2 selectivity (Hostanska et al., 2007).
Comprehensive quantification of flavonoids and salicylic acid ...
2023年8月30日 · Methanol acidified with 1% HCl was the best extraction solvent. The microLC-MS/MS method showed good linearity in a wide range of concentrations. Willow (Salix spp.) is gaining an increasing interest as a fast-growing tree with high biomass yield from low agricultural inputs, which contains potentially bioactive compounds.
[From willow bark to acetylsalicylic acid] - PubMed
Its ancestry the salicylates, including salicin and salicylic acid, are found in the bark and leaves of the willow and poplar trees. The ancient Sumerians and Egyptians, as well as Hippocrates, Celsus, Pliny the Elder, Dioscorides and Galen used these natural products as remedies for pain, fever and inflammation.
Chemical profiling and biological activities of “green” extracts of ...
2023年5月1日 · Willow bark extract (Salix spp., Salicaceae) has been used since ancient times as an analgesic, antipyretic and anti-inflammatory agent. In this paper, microwave-assisted extraction (MAE) was applied for the extraction of little-studied leaves and bark of six different species of the genus Salix with potential medicinal value.
From plant extract to molecular panacea: a commentary on Stone …
2015年4月4日 · In 1897, Bayer chemists produced a stable acetylated salicylate from salicylic acid derived from the meadowsweet plant rather than willow bark. The compound named aspirin was a contraction of the two words acetyl and Spirsäure— or salicylic acid.
Seed Treatment with Biostimulants Extracted from Weeping Willow
2021年7月15日 · In 3 days, seed treatment with salicylic acid and willow extract increased the shoot FW of maize seedlings 130% and 225%, respectively. The root area was, on average, enhanced by 43% with SA and 87% with willow extract applications.