Chondrocytes: anatomy and function - Kenhub
2024年3月19日 · Chondrocytes are the primary cells found in the extracellular matrix of cartilage. Learn more here at Kenhub!
Histology, Chondrocytes - StatPearls - NCBI Bookshelf
2023年4月17日 · Chondrocytes maintain the extracellular matrix (ECM) and produce the cartilage matrix. Surrounded by collagenous fibers, chondrocytes release substances to make cartilage strong yet flexible. In general, chondrocytes are found within intervertebral discs and in any form of articular cartilage (AC).
Chondrocyte - Wikipedia
Chondrocytes (/ ˈkɒndrəsaɪt, - droʊ -/, [1] from Greek χόνδρος (chondros) 'cartilage' and κύτος (kytos) 'cell') are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans.
Chondrocyte - an overview | ScienceDirect Topics
Chondrocytes are highly specialized cells that differentiate from clusters of mesenchymal cells during skeletal embryogenesis. The chondrocyte synthesizes and secretes the components of the extracellular matrix, primarily proteoglycans and type II collagen.
Chondrocyte Homeostasis and Differentiation: Transcriptional …
Chondrocytes are responsible for the synthesis and turnover of the ECM, in which the major macromolecular components are collagen, proteoglycans, and non-collagen proteins. The crosstalk between chondrocytes and the ECM plays several relevant roles in …
Chondrogenesis, chondrocyte differentiation, and articular cartilage ...
Chondrocytes, which comprise the only cellular component of articular cartilage, have different morphologies ranging from more flattened at the surface to rounder and larger in the deeper zones.
Molecular Mechanisms of Chondrocyte Proliferation and …
2021年5月27日 · Chondrocytes are the only cell type (accounting for 1%) in cartilage tissue and secrete growth factors and enzymes to regulate extracellular matrix (ECM) synthesis. They further embed themselves in ECM to form cartilage (Jiang and Tuan, 2014).
The art of building bone: emerging role of chondrocyte-to …
2018年6月14日 · This review focuses on the emerging models of chondrocyte-to-osteoblast transdifferentiation and their implications for the treatment of skeletal diseases as well as the possible signaling ...
Chondrocyte - an overview | ScienceDirect Topics
The chondrocyte is one of a number of well-defined cell types in developing bone. Chondrocytes are the constituent cells of cartilage, and through their function in endochondral ossification—the process by which most vertebrate bones are formed—play a central role in determining the rate of bone growth ( Hunziker, 1994 ).
Single-cell transcriptomic analysis of chondrocytes in cartilage and ...
Here, we constructed a single-cell transcriptomic atlas of chondrocytes in healthy cartilage and identified nine chondrocyte subsets including homeostatic chondrocytes, proliferate fibrochondrocytes, and hypertrophic chondrocytes (HTC).