Isavuconazole: Uses, Interactions, Mechanism of Action
Isavuconazole is an triazole antifungal with broad spectrum of activity and good safety profile 1. It is approved by the FDA and EMA for the treatment of invasive aspergillosis and mucormycosis. It works by inhibiting fungal cell membrane synthesis.
Isavuconazonium - Wikipedia
Isavuconazonium, sold under the brand name Cresemba, is a systemic antifungal medication of the triazole class which is used to treat invasive aspergillosis and mucormycosis. [9][7][8][12] It is used as the sulfate. [9] . It is taken by mouth or given via injection into a vein. [9]
Cresemba: Uses, Dosage, Side Effects, Warnings - Drugs.com
2023年12月21日 · Cresemba (isavuconazonium sulfate) is an antifungal medication that may be used to treat invasive fungal infections caused by aspergillosis or mucormycosis in adults and children. It is available as a capsule or as an injection for intravenous administration with the following restrictions:
Isavuconazole: Mechanism of Action, Clinical Efficacy, and …
Isavuconazole, a second-generation broad-spectrum triazole with activity against yeasts, dimorphic fungi, and molds, has a favorable safety profile and predictable pharmacokinetics. Patients typically tolerate isavuconazole well with fewer drug–drug interactions.
Isavuconazonium Uses, Side Effects & Warnings - Drugs.com
2024年1月22日 · Isavuconazonium is used to treat infections caused by certain types of fungus (aspergillosis or mucormycosis). Isavuconazonium may also be used for purposes not listed in this medication guide.
Isavuconazole: Mechanism of Action, Clinical Efficacy, and ... - PubMed
2020年11月29日 · Isavuconazole, a second-generation broad-spectrum triazole with activity against yeasts, dimorphic fungi, and molds, has a favorable safety profile and predictable pharmacokinetics. Patients typically tolerate isavuconazole well with fewer drug-drug interactions.
Isavuconazole for the treatment of invasive aspergillosis and ...
One of the most recent additions to the antifungal armamentarium is isavuconazole (ISZ), a novel triazole agent that has shown good clinical efficacy against IA and mucormycosis. 18–20 This article provides an overview of this new agent, data on its efficacy in vitro and in vivo, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and po...
New Perspectives on Antimicrobial Agents: Isavuconazole
Isavuconazole is the newest of the clinically available advanced generation triazole antifungals and is active against a variety of yeasts, molds, and dimorphic fungi. Its current FDA-approved indications include the management of invasive ...
Isavuconazole: A Review in Invasive Aspergillosis and Mucormycosis
Isavuconazole is a second-generation triazole with activity against a broad spectrum of clinically important fungi. Its water-soluble prodrug, isavuconazonium sulfate (Cresemba ®), available in interchangeable intravenous and oral formulations, is approved in the USA and EU for the treatment of adults with invasive aspergillosis and ...
Isavuconazonium Monograph for Professionals - Drugs.com
2024年8月30日 · Antifungal; azole (triazole derivative); prodrug of isavuconazole. Treatment of invasive aspergillosis; designated an orphan drug by FDA for this indication. IDSA considers IV voriconazole the drug of choice for primary treatment of invasive aspergillosis; amphotericin B and isavuconazonium recommended as alternatives for primary treatment.