The spatial transcriptomic landscape of the healing mouse
2022年2月11日 · Overall, we provide a publicly available resource defining principles of transcriptomic regionalization of the colon during mucosal healing and a framework to develop and progress further...
Vasculature in the mouse colon and spatial relationships with the ...
2023年6月2日 · In the mouse colon, the mucosa had denser capillary networks than the muscle layers. The mucosal capillary rings in the proximal colon surrounded the mucosal crypts individually and some areas had doubled layers, compared to …
Transplantation of intestinal organoids into a mouse model of …
2022年2月2日 · In this assay, epithelial injury is initiated at the distal part of colon by the administration of dextran sulfate sodium, and organoids are infused into the luminal space via the anus.
Efficient enzyme-free method to assess the development and
2024年5月14日 · Mechanical disruption of mouse colon results in higher immune cell yields than enzymatic digestion, without impacting viability.
Single-cell atlas of the aging mouse colon - ScienceDirect
2022年5月20日 · Utilizing single-cell RNA sequencing (scRNAseq), we show that the mouse colonic epithelium has distinct transcriptional and cell population differences between compartments (cecum, proximal (ProxCol) and distal colon (DistCol)) during aging and characterized the changes to the GALT immune cells.
Unique Neural Circuit Connectivity of Mouse Proximal, Middle, …
2022年1月1日 · We include regional comparisons between quantitative measures in mouse and human colon that represent an important advance in showing the usefulness and relevance of the mouse system for translation to the human colon.
Single cell and spatial transcriptomics of mouse colon
This study contains single cell and spatial transcriptomics data for healthy mouse colon samples. It contains 17512 single cell profiles from 6 mice and SlideSeq-V2 profiles from 4 different mice.
A guide to histomorphological evaluation of intestinal inflammation …
2014年7月15日 · Samples of all parts of the intestinal tract from well-established mouse models of intestinal inflammation were evaluated from hematoxylin/eosin-stained sections and specific observations confirmed by subsequent immunohistochemistry.
An intravital window to image the colon in real time
2019年12月11日 · Performing intravital imaging of the colon in mouse models is challenging due to the colon’s anatomic location and motility.
Mouse models for human intestinal microbiota research: a critical ...
2017年11月9日 · Moreover, the human colon is segmented, with pouches called haustra, while the mouse colon has a smooth serosal appearance. The proximal colon of the mouse has a mucosa with transverse folds.