Protein kinase C - Wikipedia
In cell biology, protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins
Protein Kinase C: Structure, Function, and Regulation (*)
Protein kinase C is regulated by two distinct mechanisms: by phosphorylation which regulates the active site and subcellular localization of the enzyme, and by second messengers which promote protein kinase C's membrane association and resulting pseudosubstrate exposure.
Protein kinase C in the immune system: from signalling to ...
Protein kinase C (PKC) form a key family of enzymes involved in signalling pathways that specifically phosphorylates substrates at serine/threonine residues. Phosphorylation by PKC is important in regulating a variety of cellular events such as cell proliferation and the regulation of gene expression.
Protein Kinase C - an overview | ScienceDirect Topics
Protein kinase C (PKC) is a collective name for members of a relatively diverse family of protein kinases most closely associated with the PI signaling system. PKC is a multifunctional Ser/Thr kinase capable of modulating many cellular processes, including exocytosis and endocytosis of neurotransmitter vesicles, neuronal plasticity, gene ...
Protein Kinase C - an overview | ScienceDirect Topics
Protein kinase C (PKCs) is an isoenzyme family of at least 12 serine/threonine kinases primarily involved in intracellular transduction of proliferative, apoptotic, differentiating, and functional signals to the nucleus [11].
The Life and Death of Protein Kinase C - PMC
Protein kinase C (PKC) is a family of kinases that plays diverse roles in many cellular functions, notably proliferation, differentiation, and cell survival. PKC is processed by phosphorylation and regulated by cofactor binding and subcellular localization.
Activators and Inhibitors of Protein Kinase C (PKC): Their ...
Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kinase, is classed into three subfamilies based on their structural and activation characteristics: conventional or classic PKC isozymes (cPKCs; α, βI, βII, and γ), novel or non-classic PKC isozymes (nPKCs; δ, ε, η, and θ), and atypical PKC isozymes (aPKCs; ζ ...
Protein Kinase C - an overview | ScienceDirect Topics
Protein kinase C is a serine/threonine kinase that is part of numerous pathways critical for memory storage, synaptic remodeling, and neuronal repair.
Protein kinase C isoenzymes: a review of their structure ...
Protein kinase C (PKC) is a multifunctional, cyclic nucleotide-independent protein kinase that phosphorylates serine and threonine residues in many target proteins. This enzyme was identified in bovine cerebellum by Nishizuka and co-workers (Takai et al., 1977; Inoue et al., 1977) as a protein kinase that phosphorylated histone and protamine ...