Vaccenic acid - Wikipedia
Vaccenic acid is a naturally occurring trans fatty acid and an omega-7 fatty acid. It is the predominant kind of trans-fatty acid found in human milk , in the fat of ruminants , and in dairy products such as milk , butter , and yogurt .
Nature重磅：陈静/何川/迟洪波团队证实，牛肉及乳制品中的这种 …
2023年11月23日 · 该研究表明，饮食来源（牛羊肉及乳制品）的反式十八碳烯酸（TVA）在体内直接促进CD8+ T细胞功能和抗肿瘤免疫。 该研究还显示，血液中循环反式十八碳烯酸（TVA）水平较高的癌症患者对免疫疗法的反应更好，这表明它有潜力作为一种营养补充剂来帮助癌症的临床治疗。 论文共同通讯作者陈靖教授表示，有许多研究试图解读饮食与人类健康之间的联系，但由于人们吃的食物种类繁多，很难理解其中的潜在机制。 但如果我们只关注食物中的营养物质及其 …
Human health benefits of vaccenic acid - PubMed
VA is the only known dietary precursor of c9,t11 conjugated linoleic acid (CLA), but recent data suggest that consumption of this trans fat may impart health benefits beyond those associated with CLA. The health risks associated with consumption of diets high in trans fats from industrially produced hydrogenated fats are well documented.
Vaccenic Acid - an overview | ScienceDirect Topics
Vaccenic acid (VA) is a monounsaturated omega-7 fatty acid that is also classified as a trans fatty acid (trans-11-18:1n7). It is a positional and geometric isomer of oleic acid.
Mechanisms of Action of trans Fatty Acids - PMC - National …
2019年11月29日 · Structure of the geometric isomers of C18 fatty acids showing elaidic and vaccenic acids with a trans double bond, oleic acid with a cis double bond, and the fully saturated stearic acid. Evidence on the potential detrimental effects of industrial trans fatty acids first emerged in the 1950s.
Vaccenic Acid - an overview | ScienceDirect Topics
Vaccenic acid, the most significant trans -fatty acid of good milk fat, is partially metabolised into cis 9, trans 11 CLA in the human tissues by Δ9-desaturation (Kuhnt et al., 2006a).
Trans -vaccenic acid reprograms CD8 + T cells and anti-tumour
2023年11月22日 · Here we use a blood nutrient compound library-based screening approach to demonstrate that dietary trans -vaccenic acid (TVA) directly promotes effector CD8 + T cell function and anti-tumour...
Vaccenic acid suppresses intestinal inflammation by increasing ...
Vaccenic acid (VA), the predominant ruminant-derived trans fat in the food chain, ameliorates hyperlipidemia, yet mechanisms remain elusive. We investigated whether VA could influence tissue endocannabinoids (ECs) by altering the availability of their biosynthetic precursor, arachidonic acid (AA), in membrane phospholipids (PLs).
Human health benefits of vaccenic acid - Applied Physiology, …
2009年9月22日 · VA is the only known dietary precursor of c9,t11 conjugated linoleic acid (CLA), but recent data suggest that consumption of this trans fat may impart health benefits beyond those associated with CLA.
Vaccenic Acid - an overview | ScienceDirect Topics
Vaccenic Acid is a precursor to Conjugated Linoleic Acid (CLA) that can be converted by an enzyme in humans. It is found in nonconjugated ruminant fats and may offer health benefits such as antiobesity and anticarcinogenic effects.