Peimine (Verticine，贝母甲素) - 仅供科研 | 抗炎剂 | MCE
Peimine (Verticine; Dihydroisoimperialine) is an orally active natural product. Peimine has anti-inflammatory, analgesic and cough relieving effects. Peimine can be used in cancer and inflammation related research.
Peimine, an Anti-Inflammatory Compound from Chinese Herbal …
Oct 19, 2021 · Peimine (Pm), an anti-inflammatory compound from Fritillaria, is known to inhibit some voltage-dependent ion channels and muscarinic receptors, but its interaction with ligand-gated ion channels remains unexplored. We have studied if Pm affects nicotinic acetylcholine receptors (nAChRs), since they play broad functional roles, both in the ...
Peimine | C27H45NO3 | CID 131900 - PubChem
Peimine | C27H45NO3 | CID 131900 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Peimine, an Anti-Inflammatory Compound from Chinese Herbal …
Mar 29, 2022 · Peimine (Pm), an anti-inflammatory compound from Fritillaria, is known to inhibit some voltage-dependent ion channels and muscarinic receptors, but its interaction with ligand-gated ion channels remains unexplored.
Peimine, an Anti-Inflammatory Compound from Chinese Herbal
Oct 19, 2021 · Peimine (Pm), an anti-inflammatory compound from Fritillaria, is known to inhibit some voltage-dependent ion channels and muscarinic receptors, but its interaction with ligand-gated ion channels remains unexplored. We have studied if Pm affects nicotinic acetylcholine receptors (nAChRs), since they play broad functional roles, both in the ...
Peimine, a main active ingredient of - ScienceDirect
Jun 1, 2016 · Peimine is one of active ingredients of Fritillaria. Using the patch-clamp technique, we profiled the action of Peimine against selected ion channels stably expressed in HEK 293 cell lines. Our data indicated that Peimine was not only able to block the Nav1.7 ion channel but also preferably inhibited the Kv1.3 ion channel.
Peimine, a main active ingredient of Fritillaria, exhibits anti ...
Peimine is one of active ingredients of Fritillaria. Using the patch-clamp technique, we profiled the action of Peimine against selected ion channels stably expressed in HEK 293 cell lines. Our data indicated that Peimine was not only able to block the Nav1.7 ion channel but also preferably inhibited the Kv1.3 ion channel.
Identification of the Molecular Mechanisms of Peimine in the …
Peimine (also known as verticine) is the major bioactive and characterized compound of Fritillariae Thunbergii Bulbus, a traditional Chinese medicine that is most frequently used to relieve a cough. Nevertheless, its molecular targets and mechanisms ...
Peimine，一种来自中草药提取物的抗炎化合物，调节肌肉型烟碱 …
Peimine (Pm) 是一种来自贝母的抗炎化合物，已知可抑制一些电压依赖性离子通道和毒蕈碱受体，但其与配体门控离子通道的相互作用仍未得到探索。 我们研究了 Pm 是否影响烟碱型乙酰胆碱受体 (nAChR)，因为它们在神经系统和非神经元组织中都发挥着广泛的功能作用。
Pharmacodynamics and Cellular Uptake of Peimine and Peiminine …
Peimine and peiminine are isosteroidal alkaloids with multiple biological activities, such as anticancer and anti-inflammatory activities, but their cellular uptake and pharmacodynamics are unclear. In this study, a rapid and sensitive ...