Spermine - Wikipedia
Spermine is a polyamine involved in cellular metabolism that is found in all eukaryotic cells. The precursor for synthesis of spermine is the amino acid ornithine. It is an essential growth factor in some bacteria as well. It is found as a polycation at physiological pH.
Spermine (NSC 268508，精胺) - 仅供科研 | 内源性代谢物 | MCE
Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects.
精胺 - 百度百科
精胺是含有两个氨基和两个亚氨基的多胺类物质，在生物体内由腐胺（丁二胺）和S-腺苷蛋氨酸经多种酶催化后生成。 它与亚精胺都存在于细菌和大多数动物细胞中，是促进细胞增殖的重要物质。 在酸性条件下，它呈现出多阳离子多胺类特性，并能与病毒与细菌中DNA结合。 使DNA分子具有更大的稳定性与柔韧性，也是细胞培养液中必要组分之一。
The function of spermine - PubMed
This review describes these alterations and focuses on the roles of spermine which may contribute to these phenotypes including reducing damage due to reactive oxygen species, protection from stress, permitting correct current flow through inwardly rectifying K(+) channels, controlling activity of brain glutamate receptors involved in learning ...
精胺 - 维基百科，自由的百科全书
精胺 （Spermine）是存在于所有 真核细胞 中的一种 多胺 类物质。 呈 碱性，在生理 pH 下以多质子化的形式存在。 荷兰科学家 列文虎克 （Antonie Philips van Leeuwenhoek）早在1678年就已从人的 精液 中得到了磷酸精胺结晶。 [1] 1888年德国化学家 Albert Ladenburg 和 Abel 首先将其称为“精胺”（德文 Spermin）。 [2] 1926年英国的 Dudley 等 [3] 与德国的 Wrede 等 [4] 同时提出了精胺的正确化学结构。
Spermine | C10H26N4 | CID 1103 - PubChem
Spermine is a polyamine, a small organic cations that is absolutely required for eukaryotic cell growth. Spermine, is normally found in millimolar concentrations in the nucleus. Spermine functions directly as a free radical scavenger, and forms a variety of adducts that prevent oxidative damage to DNA.
精胺的生理应用与合成 - ChemicalBook
2024年1月3日 · 精胺（Spermine）是一种生物活性分子，属于多胺类化合物。 它是由四个氨基乙胺分子与一个丙二胺分子通过碳氮键连接而形成的。 它含有两个氨基和两个亚氨基的多胺类物质，在生物体内由腐胺(丁二胺)和S‑腺苷蛋氨酸经多种酶催化后生成，它与亚精胺都存在于 ...
Functional identification of bacterial spermine, thermospermine ...
2024年5月1日 · We functionally identify for the first time bacterial spermine synthases, derived from phyla Bacillota, Rhodothermota, Thermodesulfobacteriota, Nitrospirota, Deinococcota, and Pseudomonadota.
The function of spermine - Pegg - 2014 - IUBMB Life - Wiley …
2014年1月6日 · Spermine is the most strongly basic polyamine and the great majority of the cellular spermine is bound to acidic sites on macromolecules. Release of spermine from these sites is likely to induce the polyamine back-conversion/catabolic pathways that generate spermidine (Fig. 1 A).
Spermine - an overview | ScienceDirect Topics
Spermine is an organic cation produced during biological metabolism, which is important to the regulation of nucleic acid and protein synthesis.
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