Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as ... - Nature
2024年2月15日 · Alopecia areata (AA) is a common non-scarring hair loss condition driven by the collapse of immune privilege and oxidative stress. The role of ferroptosis, a type of cell death linked to...
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Integrated single-cell chromatin and transcriptomic analyses of …
2023年7月27日 · We generated matched single-cell chromatin profiles and transcriptomes from scalp tissue from healthy controls and patients with alopecia areata, identifying diverse cell types of the hair ...
Epidemiology and burden of alopecia areata: a systematic review
Alopecia areata (AA) is a common, clinically heterogenous, immune-mediated, non-scarring hair loss disorder. 1 – 3 The disease may be limited to one or more discrete, well-circumscribed round or oval patches of hair loss on the scalp or body, or it may affect the entire scalp (alopecia totalis) or the entire body (alopecia universalis). 1, 2 ...
Identification of Potential Hub Genes in Alopecia Areata
4 天之前 · Alopecia areata (AA) is an immune-mediated chronic alopecia disease, but its specific pathogenesis is unclear. Gene expression data for AA patients (AAs) and healthy controls (HCs) were retrieved from the GEO database, and the differentially expressed genes (DEGs) between AAs and HCs were identified. Then, GO, KEGG and GSEA analysis were performed.
Combined Diet and Supplementation Therapy Resolves Alopecia Areata …
Alopecia areata (AA) is a common autoimmune condition resulting in spot baldness and, rarely, more extensive hair loss. There is an association between both the incidence and the severity of AA and several micronutrients, including vitamin D and zinc. This case reports an eight-year-old male diagnosed with AA and treated with a diet and ...
Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as
2024年2月15日 · Alopecia areata (AA) is a common non-scarring hair loss condition driven by the collapse of immune privilege and oxidative stress. The role of ferroptosis, a type of cell death linked to oxidative stress, in AA is yet to be explored, …
Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as …
2024年2月15日 · Five overlapping genes—ALOX15, SLC40A1, LCN2, CREB5, and SLC7A11—were identified as potential diagnostic markers for AA. AA, alopecia areata, SVM-RFE, support vector machine-recursive feature elimination; LASSO, least absolute shrinkage and selection operator;)
Whole exome sequencing in Alopecia Areata identifies rare
2022年2月10日 · Here, we identify rare variants contributing to Alopecia Areata using a whole exome sequencing and gene-level burden analyses approach on 849 Alopecia Areata patients compared to 15,640...