ARG1 Gene - GeneCards | ARGI1 Protein | ARGI1 Antibody
网页2024年8月5日 · GeneCards Summary for ARG1 Gene. ARG1 (Arginase 1) is a Protein Coding gene. Diseases associated with ARG1 include Argininemia and Urea Cycle Disorder. Among its related pathways are superpathway of L-citrulline metabolism and Innate Immune System.
ARG1 (gene) - Wikipedia
网页The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.
Arginase Deficiency - GeneReviews® - NCBI Bookshelf
网页2004年10月21日 · ARG1 encodes ARG1, which forms a homotrimer that requires manganese as a cofactor for catalytic activity and stability. Deficiency of arginase leads to accumulation of arginine and related, toxic compounds such as guanidinoacetate.
ARG1 gene - MedlinePlus
网页2024年2月13日 · The ARG1 gene provides instructions for producing the enzyme arginase. This enzyme participates in the urea cycle, a series of reactions that occurs in liver cells.
Arginase: shedding light on the mechanisms and opportunities ...
网页2022年10月8日 · ARG1 promotes M2 anti-inflammation response through blocking NO production from iNOS, but ARG2 induces pro-inflammatory cytokine production (TNF-α, IL-6, and MCP-1) in M1 via mitochondrial ROS ...
Functions of Arginase Isoforms in Macrophage Inflammatory ...
网页2014年10月27日 · The gene for human liver arginase (ARG1) is assigned to chromosome band 6q23. Am J Hum Genet (1986) 39:186–93. [PMC free article] [Google Scholar]
Arginase deficiency: MedlinePlus Genetics
网页Arginase deficiency is an inherited disorder that causes the amino acid arginine (a building block of proteins) and ammonia to accumulate gradually in the blood. Ammonia, which is formed when proteins are broken down in the body, is toxic if levels become too high.