B Cell Subset Analysis | ARUP Laboratories Test Directory
网页B Cell Subset Analysis. Assess B cell subsets of immunodeficiencies. Support the diagnosis of common variable immune deficiency (CVID) and assist in predicting the clinical phenotype. Assess B cell reconstitution after bone marrow or …
Peripheral B cell subsets - PMC - National Center for …
网页Naïve B cells are generally divided into three subsets, B-1 B cells, follicular B cells, and marginal zone (MZ) B cells. B-1 B cells are typically subdivided into B-1a and B-1b B cells. The origins and development of these unique subsets will be considered below following a discussion of recent developments regarding the functions of these ...
Human B-cell subset identification and changes in inflammatory …
网页2023年1月7日 · In this review we will describe the main subsets of B cells in peripheral blood and how these can be identified using flow and mass cytometry, as well as important changes in B-cell subsets in inflammatory immune mediated conditions.
Editorial: New Insights Into B Cell Subsets in Health and Disease
网页2022年2月1日 · The B cell population is made up of different B cell subsets depending on their developmental or proliferation status, location and function. B cells produce “natural” antibodies as part of innate immunity, but also generate antigen-specific immunity during adaptive immune responses.
The dynamic profile and potential function of B-cell subsets …
网页2020年9月2日 · According to their developmental trajectory, B cells can be divided into five major cell subtypes in the peripheral blood: transitional B cells (TrB cells), naive B cells,...
Comprehensive analyses of B-cell compartments across the human body ...
网页2020年12月10日 · We found striking donor-to-donor variability in the frequencies and isotype of CD27 + memory B cells (MBCs). A comprehensive antibody-based screen revealed markers of MBC and allowed identification of novel MBC subsets with distinct functions defined according to surface expression of CD69 and CD45RB.
Peripheral B cell subsets - PubMed
网页Our understanding of the origins and the biological functions of different peripheral B cell subsets continues to evolve. Some understanding has been obtained regarding the synergy between BCR-derived signals and other receptors and signaling pathways that drive the development of follicular, margin ….
Surface phenotypes of naive and memory B cells in mouse and …
网页2021年12月22日 · Zuccarino-Catania, G. V. et al. CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype. Nat. Immunol. 15, 631–637 (2014).
Comprehensive phenotyping of human peripheral blood B …
网页2021年10月18日 · In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals. A specific gating strategy is also described to clearly and univocally identify B cell subsets based on …
Human peripheral blood B-cell compartments: a crossroad in B-cell ...
网页A relatively high number of different subsets of B-cells are generated through the differentiation of early B-cell precursors into mature B-lymphocytes in the bone marrow (BM) and antigen-triggered maturation of germinal center B-cells into memory B-lymphocytes and plasmablasts in lymphoid tissues.