Tetracycline | C22H24N2O8 | CID 54675776 - PubChem
Tetracycline is a broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria. It has a role as an antimicrobial agent, an antibacterial drug, an antiprotozoal drug, a protein synthesis inhibitor and an Escherichia coli metabolite. It is a tertiary alpha-hydroxy ketone and a member of tetracyclines.
Tetracycline: Classification, Structure Activity Relationship and ...
Chemical modifications in the upper and lower regions of the structure of the tetracycline produce variably active and inactive compounds of first and second generation. Tetracycline and its analogues have basic chemical structure consisting tetracyclic naphthacene carboxamide ring system as shown in figure 1.
Tetracycline antibiotics - Wikipedia
While all tetracyclines have a common structure, they differ from each other by the presence of chloro, methyl, and hydroxyl groups. These modifications do not change their broad antibacterial activity, but do affect pharmacological properties such as half-life and binding to proteins in serum .
Tetracycline hydrochloride | C22H25ClN2O8 | CID 54704426
Tetracycline hydrochloride | C22H25ClN2O8 | CID 54704426 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Tetracyclines structures - Big Chemical Encyclopedia
The tetracyclines are a group of antibiotics having an identical 4-ring carbocycHc structure as a basic skeleton and differing from each other chemically only by substituent variation. Figure 1 shows the principal tetracycline derivatives now used commercially.
Tetracycline | C22H24N2O8 - ChemSpider
ChemSpider record containing structure, synonyms, properties, vendors and database links for Tetracycline, 60-54-8, Achromycin, OFVLGDICTFRJMM-WESIUVDSSA-N
Tetracycline - an overview | ScienceDirect Topics
Some early generations of tetracycline derivatives had three hydroxyl groups on the B ring, while one hydroxyl group was eliminated from molecules in later generations. The rest of the structure of tetracycline is indispensable for the molecule to bind to the ribosome, especially the dimethyl amino group on the A ring [50]. Although some of the ...
Chemical structures of various tetracycline antibiotics. a Structure …
... core structure of an active tetracycline antibiotic includes a four-ring system (labeled A-D, Fig. 1) where ring D is aromatic but rings A, B, and C include saturated carbon centers. As a...
Chemical structures of tetracyclines. Chemical structures of (A …
Tetracyclines (TCs) are a class of broad-spectrum antibiotics with diverse pharmacotherapeutic properties due to their various functional groups being attached to a common core structure.
Tetracycline - The molecule - Bristol
The tetracycline molecule possesses five asymmetric centers: C-4, -4a, -5a, -6, and -12a. A determination of the crystal structure of aureomycin hydrochloride has clearly defined the relative stereochemistry of these centers [22].