Cardiac Glycosides (Digoxin) - CV Pharmacology
Cardiac glycosides represent a family of compounds that are derived from the foxglove plant (Digitalis purpurea). The therapeutic benefits of digitalis were first described by William Withering in 1785. Initially, digitalis was used to treat dropsy, which is an old term for edema.
Cardiac Glycosides: Types and What They Treat - Cleveland Clinic
2022年12月8日 · Cardiac glycosides examples include digoxin (Cardoxin® and Lanoxin®), digitalis and digitoxin. They come from the digitalis (foxglove) plant, which is where they get their names. Other cardiac glycoside drugs include oleandrin, bufalin and ouabain. Digoxin is the most commonly prescribed cardiac glycoside. Who needs to have cardiac glycosides?
Digitalis Glycoside - an overview | ScienceDirect Topics
Digitalis glycosides (cardiac glycosides) are used in the treatment of congestive heart failure and cardiac arrhythmias. They affect cardiac contractility by increasing the force of contraction through inhibition of the sodium–potassium–ATPase pump.
Digoxin (oral route) - Mayo Clinic
Digoxin belongs to the class of medicines called digitalis glycosides. It is used to improve the strength and efficiency of the heart, or to control the rate and rhythm of the heartbeat. This leads to better blood circulation and reduced swelling of …
Digitalis Glycoside - an overview | ScienceDirect Topics
Digitalis refers to a class of cardioactive drugs called glycosides which exert both mechanical and electrical effects on the heart. The most commonly used digitalis preparation in current practice is digoxin.
Digitalis | Circulation - AHA/ASA Journals
1999年3月9日 · Compelling direct evidence supporting cardiac glycoside–induced increases in intracellular Na + concentration or activity ([Na +] i) has now been obtained, and the mechanism of digitalis-induced positive inotropy is known to involve an altered balance between intracellular Na + and Ca 2+.
Digitalis glycosides - PubMed
The digitalis glycosides are potent cardiovascular drugs with a low therapeutic index and a high incidence of iatrogenic complications. Digoxin is the most commonly used preparation. Common indications include rate control in atrial fibrillation, as well …
Digitalis Glycoside - an overview | ScienceDirect Topics
Digitalis glycosides are steroid derivatives that mildly increase myocardial contractility and elicit characteristic electrophysiological responses. They consist of a steroid nucleus combined with a lactone ring and sugars, and are primarily used in the management of supraventricular arrhythmias like atrial fibrillation.
digitalis_glycosides [TUSOM | Pharmwiki] - Tulane University
Digitalis glycosides are a group of chemically related compounds isolated primarily from plant sources, such as the purple and white foxglove plants (Digitalis purpurea and Digitalis lanata). Digoxin (generic, Lanoxicaps, Lanoxin ®) is the only form of digitalis glycoside available for clinical use in the USA .
Digitalis Uses, Benefits & Dosage - Drugs.com Herbal Database
2024年11月11日 · Digitalis has long been used as a treatment for heart failure in addition to a range of other traditional uses. The plant is cultivated as an ornamental. Digitalis leaf has a narrow therapeutic index, requiring close medical supervision for safe use. Traditional dosage starts at 1.5 g of leaf divided into 2 daily doses.